Archive for the ‘News’ Category

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HIV dates back to around 1900, study shows

October 4, 2008

Genetic analysis of tissue specimen recently discovered in the Democratic Republic of the Congo leads researchers to believe the virus that causes AIDS has been present for more than a century.

By Mary Engel, Los Angeles Times Staff Writer
October 2, 2008

A genetic analysis of a biopsy sample recently discovered in the Democratic Republic of the Congo has led researchers to conclude that the virus that causes AIDS has existed in human populations for more than a century, according to a study released Wednesday.

The study, led by evolutionary biologist Michael Worobey of the University of Arizona in Tucson, puts the date of origin at around 1900, which is 30 years earlier than previous analyses.

HIV-1, the most common form of the virus, is known to have originated in chimpanzees because of close genetic similarities to a simian virus. It now infects an estimated 33 million people worldwide.

But figuring out when the virus jumped species and became established in humans has been difficult. The first cases in the U.S. were recognized in 1981, and the oldest evidence of the virus is a 1959 blood sample taken from a man who lived in what was then the Belgian Congo.

To find the point of origin, the scientists relied on a well-recognized genetic technique to determine the mutation rates of different sub-types of the virus. With a known rate of mutation, researchers could then, in essence, run the clock backward to find the point where the different sub-types were the same. That common ancestor would represent the first appearance of the virus in humans before it mutated.

“The HIV virus evolves incredibly quickly,” said geneticist Bette Korber of Los Alamos National Laboratory in New Mexico, who did an analysis in 2000. “Those mutations get passed on to the next individual. So we have that evolutionary pace to enable a look backward.”

Korber’s analysis compared the 1959 blood sample and modern samples. She traced their common ancestor to roughly 1931.

The new analysis, published in the journal Nature on Wednesday, added lymph node tissue from a woman who died in 1960 in the Belgian Congo. The tissue specimen was one of more than 800 preserved in ice-cube-size blocks of paraffin at the University of Kinshasa.

The researchers compared that sample with modern strains to determine its mutation rate. Then they matched that rate with the 1959 sample, tracing their common ancestor to between 1884 and 1924.

“I’ve been trying to track down old samples like this for quite a few years now,” Worobey said. “As soon as you have that one other sequence from that same time period, it really snaps the whole evolutionary picture into sharp focus.”

The researchers surmised that the creation of colonial cities around the turn of the century was the catalyst that allowed the virus to take hold.

Dr. Steven M. Wolinsky, a co-author of the study, said that colonial cities meant not just more potential hosts for viruses living in closer quarters, but also prostitution and other high-risk behaviors for transmitting the virus.

“Urbanization was probably the main trigger,” said Wolinsky, an infectious diseases specialist at the Feinberg School of Medicine at Northwestern University in Chicago.

Jim Moore, an anthropologist at UC San Diego who was not associated with the study, said the fact that the virus could have spread unnoticed for decades is no surprise, given the mortality rates in Africa during the colonial period.

“The conditions then were horrendous in terms of how Africans were treated,” he said. “People dying of AIDS would have been part of the background.”

reference:http://www.latimes.com/news/nationworld/nation

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China’s “spacewalker” heads backs to earth

September 28, 2008

By GILLIAN WONG, Associated Yahoo! Press Writer.

BEIJING – Three Chinese astronauts made a jubilant return to Earth on Sunday after successfully completing the country’s first-ever spacewalk, an event the premier said was “a stride forward” in China’s space history

The spacewalk was mainly aimed at testing China’s mastery of the technology involved. The sole task of mission commander Zhai Zhigang was to retrieve a rack attached to the outside of the orbital module. He remained outside for about 13 minutes.

“It was a glorious mission, full of challenges with a successful end,” Zhai said after the Shenzhou 7 module landed under clear skies in the grasslands of China’s northern Inner Mongolia region. “We feel proud of the motherland.”

State broadcaster CCTV showed the astronauts emerge from their capsule, which floated gently down under a giant red-and-white-striped parachute, and wave at cameras as they celebrated the end of their 68-hour mission.

Zhai, Liu Boming and Jing Haipeng stayed inside for about 46 minutes to adapt to Earth’s gravity before crawling out of the narrow entrance. They were declared healthy after medical examinations inside the module.

“This mission’s success is a milestone; a stride forward,” Premier Wen Jiabao said at mission control.

Saturday’s space walk, which was broadcast live and watched by crowds gathered around outdoor television screens, further stoked national pride one month after the close of the Beijing Olympics.

“A small step by Zhai Zhigang in space is a big step in the history of the Chinese nation,” said a commentary by the official Xinhua News Agency carried Sunday by the Beijing Daily newspaper.

On most newspaper front pages were pictures of Zhai clutching a Chinese flag as he hovered in space outside the Shenzhou 7 vessel, alongside photos of Chinese President Hu Jintao on a telephone as he spoke to the astronauts.

While successful, the spacewalk wasn’t without anxious moments.

Zhai, a 41-year-old fighter pilot, appeared to struggle with the hatch and a fire alarm was triggered in the orbiter as he began the spacewalk.

Wang Zhaoyao, deputy director of manned space flight, conceded that the combined effects of weightlessness and depressurization on the hatch opening operation hadn’t been fully anticipated. He blamed a faulty sensor for the fire alarm.

The spacewalk required the astronauts to first depressurize and then repressurize the orbital module and proved the effectiveness of Zhai’s Feitian space suit, produced by China at a cost of $4.4 million. Liu wore a nearly identical Russian-made Orlan suit, according to the reports.

The spacewalk paves the way for assembling a space station from two Shenzhou orbital modules, the next major goal of China’s manned spaceflight program.

China is also pursuing lunar exploration and may attempt to land a man on the moon in the next decade — possibly ahead of NASA’s 2020 target date for returning to the moon.

China launched its first manned mission, Shenzhou 5, in 2003, becoming only the third country after Russia and the United States to launch a man into space. That was followed by a two-man mission in 2005.

reference:http://news.yahoo.com/s/ap/20080928/ap_on_re_as/as_china_space

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What Happens When We Die?

September 24, 2008

By M.J. STEPHEY -  Tue Sep 23, 6:40 PM ET

A fellow at New York City’s Weill Cornell Medical Center, Dr. Sam Parnia is one of the world’s leading experts on the scientific study of death. Last week Parnia and his colleagues at the Human Consciousness Project announced their first major undertaking: a 3-year exploration of the biology behind “out-of-body” experiences. The study, known as AWARE (AWAreness during REsuscitation), involves the collaboration of 25 major medical centers through Europe, Canada and the U.S. and will examine some 1,500 survivors of cardiac arrest. TIME spoke with Parnia about the project’s origins, its skeptics and the difference between the mind and the brain.

What sort of methods will this project use to try and verify people’s claims of “near-death” experience?

When your heart stops beating, there is no blood getting to your brain. And so what happens is that within about 10 sec., brain activity ceases – as you would imagine. Yet paradoxically, 10% or 20% of people who are then brought back to life from that period, which may be a few minutes or over an hour, will report having consciousness. So the key thing here is, Are these real, or is it some sort of illusion? So the only way to tell is to have pictures only visible from the ceiling and nowhere else, because they claim they can see everything from the ceiling. So if we then get a series of 200 or 300 people who all were clinically dead, and yet they’re able to come back and tell us what we were doing and were able see those pictures, that confirms consciousness really was continuing even though the brain wasn’t functioning.

How does this project relate to society’s perception of death?

People commonly perceive death as being a moment – you’re either dead or you’re alive. And that’s a social definition we have. But the clinical definition we use is when the heart stops beating, the lungs stop working, and as a consequence the brain itself stops working. When doctors shine a light into someone’s pupil, it’s to demonstrate that there is no reflex present. The eye reflex is mediated by the brain stem, and that’s the area that keeps us alive; if that doesn’t work, then that means that the brain itself isn’t working. At that point, I’ll call a nurse into the room so I can certify that this patient is dead. Fifty years ago, people couldn’t survive after that.

How is technology challenging the perception that death is a moment?

Nowadays, we have technology that’s improved so that we can bring people back to life. In fact, there are drugs being developed right now – who knows if they’ll ever make it to the market – that may actually slow down the process of brain-cell injury and death. Imagine you fast-forward to 10 years down the line; and you’ve given a patient, whose heart has just stopped, this amazing drug; and actually what it does is, it slows everything down so that the things that would’ve happened over an hour, now happen over two days. As medicine progresses, we will end up with lots and lots of ethical questions.

But what is happening to the individual at that time? What’s really going on? Because there is a lack of blood flow, the cells go into a kind of a frenzy to keep themselves alive. And within about 5 min. or so they start to damage or change. After an hour or so the damage is so great that even if we restart the heart again and pump blood, the person can no longer be viable, because the cells have just been changed too much. And then the cells continue to change so that within a couple of days the body actually decomposes. So it’s not a moment; it’s a process that actually begins when the heart stops and culminates in the complete loss of the body, the decompositions of all the cells. However, ultimately what matters is, What’s going on to a person’s mind? What happens to the human mind and consciousness during death? Does that cease immediately as soon as the heart stops? Does it cease activity within the first 2 sec., the first 2 min.? Because we know that cells are continuously changing at that time. Does it stop after 10 min., after half an hour, after an hour? And at this point we don’t know.

What was your first interview like with someone who had reported an out-of-body experience?

Eye-opening and very humbling. Because what you see is that, first of all, they are completely genuine people who are not looking for any kind of fame or attention. In many cases they haven’t even told anybody else about it because they’re afraid of what people will think of them. I have about 500 or so cases of people that I’ve interviewed since I first started out more than 10 years ago. It’s the consistency of the experiences, the reality of what they were describing. I managed to speak to doctors and nurses who had been present who said these patients had told them exactly what had happened, and they couldn’t explain it. I actually documented a few of those in my book What Happens When We Die because I wanted people to get both angles – not just the patients’ side but also the doctors’ side – and see how it feels for the doctors to have a patient come back and tell them what was going on. There was a cardiologist that I spoke with who said he hasn’t told anyone else about it because he has no explanation for how this patient could have been able to describe in detail what he had said and done. He was so freaked out by it that he just decided not to think about it anymore.

Why do you think there is such resistance to studies like yours?

Because we’re pushing through the boundaries of science, working against assumptions and perceptions that have been fixed. A lot of people hold this idea that, well, when you die, you die; that’s it. Death is a moment – you know you’re either dead or alive. All these things are not scientifically valid, but they’re social perceptions. If you look back at the end of the 19th century, physicists at that time had been working with Newtonian laws of motion, and they really felt they had all the answers to everything that was out there in the universe. When we look at the world around us, Newtonian physics is perfectly sufficient. It explains most things that we deal with. But then it was discovered that actually when you look at motion at really small levels – beyond the level of the atoms – Newton’s laws no longer apply. A new physics was needed, hence, we eventually ended up with quantum physics. It caused a lot of controversy – even Einstein himself didn’t believe in it.

Now, if you look at the mind, consciousness, and the brain, the assumption that the mind and brain are the same thing is fine for most circumstances, because in 99% of circumstances we can’t separate the mind and brain; they work at the exactly the same time. But then there are certain extreme examples, like when the brain shuts down, that we see that this assumption may no longer seem to hold true. So a new science is needed in the same way that we had to have a new quantum physics. The CERN particle accelerator may take us back to our roots. It may take us back to the first moments after the Big Bang, the very beginning. With our study, for the first time, we have the technology and the means to be able to investigate this. To see what happens at the end for us. Does something continue?

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Palin e-mail hack details emerge

September 19, 2008

Mrs Palin is being investigated for her
conduct as governor of Alaska

Details of how an e-mail account of US Republican vice-presidential candidate Sarah Palin was hacked have emerged.

Following the hack, screenshots of Mrs Palin’s messages, inbox, pictures and address book were posted to the Wikileaks whistle-blowing site.

It is thought the attackers exploited the password resetting system of Yahoo’s e-mail service.

Details about Mrs Palin’s life pulled from public sources reportedly helped defeat security questions.

Formal investigation

Information from Wikipedia and other online databases helped to establish Mrs Palin’s date of birth, zip code and other personal information.

Armed with this, the attackers convinced the Yahoo password re-setting system they warranted access and allowed them to re-set the password and then get at the account.

In an official statement Yahoo said: “Yahoo treats issues of security and privacy very seriously.”

It added: “To protect the privacy of our users, we are not able to comment on the details of a specific user account.”

“Generally, if Yahoo! receives reports that an account has been compromised, we investigate for suspicious activity and take appropriate action,” the company said.

The attackers broke into Mrs Palin’s gov.palin@yahoo.com e-mail account. This account and another, gov.sarah@yahoo.com, owned by Mrs Palin have now been deleted.

The FBI and the US Secret Service have now begun a formal investigation into the attack and who may have been behind it.

The hackers used the CTunnel proxy service which routes web browsing through an intermediary to obscure where the attackers were based.

However, the screenshots for the attack reveal the original web address used by the proxy which may help investigators track down the miscreants.

It has been reported that records from the CTunnel proxy service are being sought by the FBI.

The attack on the e-mail account comes as questions are being asked about whether Mrs Palin used her personal e-mail accounts to carry out state business.

US law states that all e-mails relating to the official business of government must be archived and not destroyed. However, it does allow for personal e-mails to be deleted.

Mrs Palin is being investigated in Alaska for alleged abuse of power while governor of the state.

reference:http://news.bbc.co.uk/2/hi/technology/7624809.stm

pictures:http://wikileaks.org/wiki/Sarah_Palin_Yahoo_inbox_2008

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Obama win preferred in world poll

September 11, 2008

Most thought US relations would get better under a president Obama

Some 30% of Americans expected relations to improve under Mr McCain

People outside the US would prefer Barack Obama to become US president ahead of John McCain, a BBC World Service poll suggests.

Democrat Mr Obama was favoured by a four-to-one margin across the 22,500 people polled in 22 countries.

In 17 countries, the most common view was that US relations with the rest of the world would improve under Mr Obama.

If Republican Mr McCain were elected, the most common view was that relations would remain about the same.

The poll was conducted before the Democratic and Republican parties held their conventions and before the headline-grabbing nomination of Sarah Palin as Mr McCain’s running mate.

BBC diplomatic correspondent Jonathan Marcus says the results could therefore be a reflection of the greater media focus on Mr Obama as he competed for the presidential candidacy against Hillary Clinton.

The margin of those in favour of Mr Obama winning November’s US election ranged from 9% in India to 82% in Kenya, which is the birthplace of the Illinois senator’s father.

On average 49% preferred Mr Obama to 12% in favour of Mr McCain. Nearly four in 10 of those polled did not take a view.

On average 46% thought US relations with the world would improve with Mr Obama in the White House, 22% that ties would stay the same, while seven per cent expected relations to worsen.

Only 20% thought ties would get better if Mr McCain were in the Oval Office.

The expectation that a McCain presidency would improve US relations with the world was the most common view, by a modest margin, only in China, India and Nigeria.

But across the board, the largest number – 37% – thought relations under a president McCain would stay the same, while 16% expected them to deteriorate.

In no country did most people think that a McCain presidency would worsen relations.

Oddly, in Turkey more people thought US relations would worsen with an Obama presidency than under Mr McCain, even though most Turks polled preferred Mr Obama to win.

In Egypt, Lebanon, Russia and Singapore, the predominant expectation was that relations would remain the same if Mr Obama won the election.

The countries most optimistic that an Obama presidency would improve ties were US Nato allies – Canada (69%), Italy (64%), France (62%), Germany (61%), and the UK (54%) – as well as Australia (62%), along with Kenya (87%) and Nigeria (71%).

When asked whether the election as president of the African-American Mr Obama would “fundamentally change” their perception of the US, 46% said it would while 27% said it would not.

The US public was polled separately and Americans also believed an Obama presidency would improve US ties with the world more than a McCain presidency.

Forty-six per cent of Americans expected relations to get better if Mr Obama were elected and 30% if Mr McCain won the White House.

A similar poll conducted for BBC World Service ahead of the 2004 US presidential election found most countries would have preferred to see Democratic nominee John Kerry beat the incumbent George W Bush.

At the time, the Philippines, Nigeria and Poland were among the few countries to favour Mr Bush’s re-election. All three now favour Mr Obama over Mr McCain.

In total 22,531 citizens were polled in Australia, Brazil, Canada, China, Egypt, France, Germany, India, Indonesia, Italy, Kenya, Lebanon, Mexico, Nigeria, Panama, the Philippines, Poland, Russia, Singapore, Turkey, the UAE and the UK. A parallel survey was conducted with 1,000 US adults.

Polling firm GlobeScan and the Program on International Policy Attitudes carried out the survey between July and August.

Reference: